All Sci-Fi Movies and Shows You Can Stream This Week at Home or Watch in Theaters, Including ‘Gen V’

A packed week for science-fiction fans is here, with fresh theatrical releases, day-and-date at-home premieres, and new episodes in two returning series. Whether you’re after alien encounters in the desert, post-apocalyptic treasure hunts, or campus-set super-chaos, there’s something new to queue up and catch in theaters and at home.

Below you’ll find concise rundowns focused on story and creative teams—who’s in it, who made it, and what it’s about—plus exactly when and where each title lands this week. Dates are listed in each entry along with the platform or format so you can jump straight to what you want.

‘Xeno’ (2025)

Opening in theaters on Friday, September 19, 2025, ‘Xeno’ centers on Renee, a teenager who discovers and bonds with an alien after a crash in the desert, drawing the attention of authorities and setting off a chase-and-rescue story with a creature feature twist.

Written and directed by Matthew Loren Oates, the film stars Lulu Wilson as Renee, with Omari Hardwick as Jonathan Keyes and Paul Schneider as Chase; Wrenn Schmidt and Trae Romano also appear. The production comes from Hartbeat Productions, with Kevin Hart among the producers, and features an original creature created by The Jim Henson Company; Ryan Taubert provides the score.

‘Afterburn’ (2025)

In theaters on Friday, September 19, 2025, ‘Afterburn’ adapts the Red 5 Comics series about ex-soldier-turned-treasure-hunter Jake, who ventures into a Europe devastated by a solar flare to recover items like the Mona Lisa—only to uncover a larger conflict that demands more than a simple heist.

Directed by J. J. Perry from a screenplay by Matt Johnson and Nimród Antal, the film stars Dave Bautista as Jake, Olga Kurylenko as Drea, Samuel L. Jackson as Valentine, and Kristofer Hivju in a key supporting role. The movie draws directly from the comics by Scott Chitwood, Paul Ens, and Wayne Nichols; José David Montero is director of photography, and Roque Baños composes the score.

‘Another End’ (2024)

Arriving in theaters and at home on Friday, September 19, 2025, ‘Another End’ follows Sal, a grieving man who uses a technology that temporarily hosts the consciousness of the dead in living bodies so the bereaved can say goodbye—an intimate sci-fi premise that spirals as he reconnects with his partner through a surrogate.

Written and directed by Piero Messina, the film stars Gael García Bernal as Sal, Renate Reinsve as Zoe/Ava, Bérénice Bejo as Ebe, and Olivia Williams as Juliette. The screenplay is by Messina with Giacomo Bendotti, Valentina Gaddi, and Sebastiano Melloni; it’s produced by Indigo Film with Rai Cinema and Newen Connect among distributors.

‘Unexpected Treasures’ (2025)

Streaming on Friday, September 19, 2025 on Prime Video and Apple TV (digital purchase/rental), ‘Unexpected Treasures’ is set across the Mojave around Joshua Tree, where Hartley—a struggling local—crosses paths with Sam, a charming alien fugitive. Together they try to outrun a relentless bounty hunter while unraveling a prophecy tied to the desert’s myths.

The feature directorial debut of John Paul Ungaretti, who co-wrote the script with Christina Heller, stars Olivia Blue as Hartley and two-time Emmy winner Mike Manning as Sam, with Michael Dunn (Frank), AnnaMaria DeMara (June), Lauren Han (Kaia), and Jay Whittaker in supporting roles. Produced by Desert Fishbowl, the film runs 1 hour 35 minutes.

‘Futurama’ (1999– )

New episodes land on Monday, September 15, 2025 on Hulu. Set in the 31st century, ‘Futurama’ continues to follow delivery boy-turned-spacefarer Philip J. Fry, ship captain Turanga Leela, and bending unit Bender as the Planet Express crew tackles misdeliveries, monsters, and malfunctioning science.

Created by Matt Groening and developed with David X. Cohen, the series features Billy West (Fry/Professor Farnsworth/Dr. Zoidberg), Katey Sagal (Leela), John DiMaggio (Bender), Tress MacNeille (Mom and others), Maurice LaMarche (Kif, Lrrr, Morbo), Phil LaMarr (Hermes), Lauren Tom (Amy), and David Herman (Scruffy, et al.). Executive producers include Groening, Cohen, Ken Keeler, and Claudia Katz, with animation by Rough Draft Studios.

‘Gen V’ (2023– )

Season 2 returns Wednesday, September 17, 2025 on Prime Video. Set at Godolkin University within ‘The Boys’ universe, ‘Gen V’ continues after the campus-shaking events of last season as Marie Moreau and her friends confront a militarized new order and a program that could tip the balance between humans and Supes.

Showrun by Michele Fazekas, the series stars Jaz Sinclair (Marie Moreau), Lizze Broadway (Emma Meyer/Little Cricket), Maddie Phillips (Cate Dunlap), London Thor and Derek Luh (Jordan Li), Asa Germann (Sam Riordan), and Hamish Linklater as the new dean, Cipher. The franchise is based on the comic arc ‘We Gotta Go Now’ by Garth Ennis and Darick Robertson, with recurring appearances from ‘The Boys’ characters threading the stories together.

That’s the lineup—what are you most excited to watch this week? Drop your picks and theories in the comments!