10 Most Wholesome Friendships In Anime

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Some anime friendships feel so genuine that you can trace their growth across battles, school days, and quiet moments that actually move the story forward. These pairs support each other through concrete goals, pivotal turning points, and small daily routines that reveal who they are. You can spot the strength of these bonds in how they train, travel, and make choices that affect the plot. Here are ten duos whose teamwork and loyalty shape their worlds in ways that are easy to see on screen.

Gon Freecss and Killua Zoldyck

Madhouse

Gon and Killua meet during the Hunter Exam in ‘Hunter x Hunter’ and quickly become inseparable travel partners who tackle every phase together. Their alliance drives major arcs across Heaven’s Arena, Greed Island, and the Chimera Ant conflict with shared training plans and coordinated strategies. Specific skills like Killua’s Godspeed and Gon’s Jajanken complement each other in straightforward ways during missions. The 2011 adaptation from Madhouse presents their progression step by step through clearly tracked power ups and journey milestones.

Tanjiro Kamado and Zenitsu Agatsuma

Ufotable

Tanjiro and Zenitsu form a Demon Slayer Corps trio with Inosuke in ‘Demon Slayer’ while pairing up on escort work, house investigations, and mountain operations. They rely on clear task splits where Tanjiro’s water forms anchor the fight and Zenitsu’s Thunderclap and Flash handles quick finishes. Their time at the Butterfly Mansion shows how joint rehabilitation and breathing drills lead to measurable gains. Ufotable’s adaptation highlights their teamwork with training sequences and mission briefings that mark their steady improvement.

Monkey D. Luffy and Roronoa Zoro

Toei Animation

Luffy and Zoro establish a captain and first mate partnership early in ‘One Piece’ that keeps the Straw Hat crew on course during island to island journeys. Their coordination shows up in crew rescues, ship defense, and simple rules like trusting each other’s duels without interference. Clear checkpoints such as East Blue, Water Seven, and the New World demonstrate how their responsibilities expand with the crew’s needs. Toei Animation charts this bond across thousands of minutes of screen time with shipboard routines and post battle regrouping.

Edward Elric and Alphonse Elric

Bones

Edward and Alphonse move through investigations, research stops, and field confrontations in ‘Fullmetal Alchemist: Brotherhood’ with a practical division of roles. Their search for the Philosopher’s Stone follows a consistent pattern of library work, witness interviews, and tactical retreats that keep them aligned. Alphonse’s armored body changes how they enter fights while Edward’s state alchemist access opens doors for both of them. Bones frames their progress with travel logs, debriefs, and recurring allies that document how they operate as a unit.

Shoyo Hinata and Tobio Kageyama

Production IG

Hinata and Kageyama turn a middle school rivalry into a setter spiker pairing at Karasuno in ‘Haikyu!!’ with measurable results on the court. They build quicks, synch points, and serve receive patterns through repeated drills that translate directly into match plays. Key tournaments show how scouting reports and adjustments refine their tempo attack. Production I.G presents their growth in practice montages, chalk talks, and match data that track their improvements across seasons.

Mob and Reigen Arataka

Bones

Mob and Reigen run client cases in ‘Mob Psycho 100’ where mentorship becomes a working partnership with clear steps for each job. Reigen handles negotiations and logistics while Mob provides the actual exorcism techniques, which creates consistent outcomes for their agency. School life and club activity schedules fit around their case calendar in a way that keeps Mob’s priorities balanced. Bones organizes their arc through episodic assignments, progress check ins, and public incidents that show how both benefit from the arrangement.

Ash Ketchum and Pikachu

OLM

Ash and Pikachu travel region by region in ‘Pokémon’ with a routine that includes gym challenges, field training, and tournament brackets. Their strategy evolves through move sets, item use, and mid battle switches that reflect prior experience from earlier routes. Companion rotations change but their core pairing anchors each league attempt and research stop. OLM documents this rhythm through badges, league placements, and new forms that mark consistent advancement.

Natsu Dragneel and Happy

A-1 Pictures

Natsu and Happy operate as a mobile duo in ‘Fairy Tail’ by scouting, transport, and mid air support during guild jobs. Happy’s flight extends Natsu’s reach in rescue sequences and aerial approaches, which affects how they tackle requests posted at the guild. Their mission logs range from simple deliveries to multi day battles that require quick recoveries and camp setups. A-1 Pictures stages their teamwork with job boards, payout scenes, and guild briefings that show how they function inside the larger Fairy Tail structure.

Anya Forger and Becky Blackbell

Wit Studio and Cloverworks

Anya and Becky become classmates in ‘Spy x Family’ and build a friendship that threads through school projects, exam prep, and dorm style hangouts. Their interactions at Eden Academy include study sessions, shopping trips, and parent day events that put them in the same orbit regularly. Plotlines about Stella stars and Tonitrus bolts show how they navigate school systems together. Wit Studio and CloverWorks frame their bond through campus routines and classroom beats that recur across the school year.

Seishu Handa and Naru Kotoishi

Kinema Citrus

Handa and Naru connect in ‘Barakamon’ when the calligrapher relocates to the Goto Islands and joins village life. Naru guides him through local customs, chores, and seasonal activities that fill his days with practical tasks. Their shared calendar covers fishing, festivals, and calligraphy practice that gradually structures his work output. Kinema Citrus captures this schedule with island walks, community visits, and workshop scenes that track their steady rapport.

Share your favorite anime friendships in the comments so everyone can add more heartfelt duos to the list.

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